Season 22 (2025)

Episodes: 13

Star Cast: Ellen Pompeo , Chandra Wilson , James Pickens Jr. , Kevin McKidd ,

Episodes List

Ep.1 Only the Strong Survive

Air Date: 2025-10-09

After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

Ep.2 We Built This City

Air Date: 2025-10-16

The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

Ep.3 Between Two Lungs

Air Date: 2025-10-23

A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

Ep.4 Goodbye Horses

Air Date: 2025-10-30

The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

Ep.5 Sometimes I Feel Like a Motherless Child

Air Date: 2025-11-06

Jo navigates a challenging case with a pregnant mother, while Blue and Jules care for a diabetic patient. Meanwhile, Simone treats a patient with a surprising revelation.

Ep.6 When I Crash

Air Date: 2025-11-13

Grey Sloan takes in patients following a catastrophic bus accident. Teddy and Owen have an awkward encounter, and Richard tests Bailey's patience.

Ep.7 Skyfall

Air Date: 2026-01-08

Winston and Ben fight to save Jo's life, while Teddy supports Link. Owen and Jules battle to save a young man, and Lucas forms an unexpected bond with a patient.

Ep.8 Heavy on Me

Air Date: 2026-01-15

Bailey and Owen join forces to save a tumor patient, while Richard faces an internal battle. Meanwhile, Jules struggles with her feelings for Winston.

Ep.9 Fortunate Son

Air Date: 2026-01-22

Richard continues to navigate his health. Meanwhile, Meredith and Nick are visited by Nick's estranged sister from Boston.

Ep.10 Strip That Down

Air Date: 2026-01-29

Addison Montgomery returns to Grey Sloan, seeking assistance with a patient with a neurological condition. Bailey joins Owen and Blue on a paramedic ride-along.